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About Nanobiotechnology Research Center (NBRC)PDFPrint

Following receiving the final approval from Council of expansion of medical universities and the Ministry of Health and Medical Education on Nov 11th, 2007 regarding the foundation of Nanobiotechnology research center (NBRC) - affiliated to Avicenna Research Institute (ARI) -; in Aug 17th, 2008, the authorization was also officially granted to Nanobiotechnology Research Center by the Iranian Academic Center for Education, Culture and Research (ACECR) board of trustees. This Research Center has started its activities along with the development of basic activities of Avicenna Research Institute- affiliated to ACECR- in the field of novel biological sciences and in line with short and long policy objectives of Iranian Nanotechnology Initiative Council with the pivotal idea of application of nanotechnology the diagnosis and treatment of Hard to Treat Diseases (HTDS).

The primary focus of Nanobiotechnology Research Center’s programs and activities are on:

- Becoming the hub of the scientific research meeting the needs of Iran Health Ministry using nanotechnology.

- Becoming a well-known international center for scientific research in the fields of nanobiotechnology and nanomedicine.

At present, NBRC comprises departments:

1. Nanotechnology Department

2. Recombinant Technology Department

3. Nanobiosynthesis Department

The Research Center is currently conducting several research projects regarding of its aforementioned priorities being founded by national & international resources. Of distinctive features of the NBRC, is the close cooperation of scientific staff from various disciplines of Biology and chemistry on performing research and clinical projects.

All the NBRC staffs are aimed at applying and expanding of nanotechnology into various fields of medical science including diagnosis and treatment of chronic and intractable diseases. With respect to relative newness of Nanotechnology Science and its extra rapid extension in the past two decades a broad range of investigation have been facing researchers interested in nano-technology which cannot be completely covered to be studied. Thus, the NBRC has set research priorities in the following fields

Therefore, the NBRC’s research priorities have been focused in the followed area of biotechnology and medical application of nanotechnology:

1. New systems designing for cancer diagnostic and therapy.

2. Design of controlled drug delivery system.

3. Production of recombinant pharmaceutical proteins and molecular studies using these proteins.

4. Isolation and purification of proteins or cells using new methods (e.g. magnetic particles ...).

5. Smart Nano-structures synthesis for drug delivery.

6. Chemical and biological synthesis of nanoparticles.

At present, the following technologies have been established by considering NBRC’s faculty members attempts:

1. Synthesis, of Semiconductor quantum dots (CdSe), the establishment of Functional groups and conjugation with anti breast and ovarian cancer antibody.

2. Conjugation of Nanomagnetic Particles to Monoclonal Antibodies and Peptides: Optimization and Application in Brest Cancer Diagnosis.

3. Validation and optimization of metal-ion affinity chromatography of Polyhistidine-tagged proteins using Nickel Coated Magnetic Beads.

4. Extraction and Purification of Nanomagnetic Particles from Magnetotactic Bacteria.

5. Preparation and quality evaluation of MACS columns .

Furthermore, owing to its achieved abilities, Nanobiotechnology research center, is a member of Iran High-Tech Laboratory Network (http://labsnet.ir/) and is currently providing professional laboratory services for applicants from universities and industry.

1. Assessment of cytotoxic impacts of nanoparticels.

2. Nanoparticles analysis using HPLC.

3. Synthesis and protection of nanomagnetic particles.

4. Nanoparticles analysis by DLS.

5. Cell and biomolecule purification by Magnetic-Activated Cell Sorting Column (MACS) and Metal-ion Affinity Chromatography, respectively.

Development plans in the future:

1. Patent registration for the products resulting from practical research projects.

2. Commercialization of the products resulting from nanotechnology-related projects through knowledge-based companies.

3. Development and establishment of new laboratories related to nanotechnology.

4. Recruiting of specialists in order to increase productivity.

5. Supporting and training post graduate students with PhD and MSc thesis projects related to Nanobiotechnology.

6. Becoming an exclusive research center through: Achieving the latest technologies and related disciplines, Increasing ability to conduct specialized research activities and services, Create a dynamic and capable research environment, Effective international communication, caring out new research in relevant area and training top researcher students in the latter filed.

  •  http://labsnet.ir) can receive of discount on using our Professional Laboratory services that are listed at http://labsnet.ir/labs/15. Please send your ask to Mohammad Reza Nejadmoghaddam, This e-mail address is being protected from spambots. You need JavaScript enabled to view it .

 

Head of Research Center: Dr Zohreh Mohammadi

Last Updated on Monday, 04 April 2016 07:57
 
 

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